The Skin Diary launches Age Defence Moisturising Day Cream

With broad spectrum encapsulated sunscreen, SPF 50 protection, powerful DNA repair technology and antioxidants

The Skin Diary’s Age Defence Moisturising Day Cream (RRP: €110.00)

The Skin Diary, the dermatologist-led Irish skincare brand founded by Dr. Clare Kiely, behind the cult favourite Night Repair Therapy cream, is pushing boundaries of  daytime skincare with its latest innovation, Age Defence Moisturising Day Cream. Created in collaboration with leading consultant dermatologists, including Professor Chris Griffiths OBE, this luxurious formula provides triple action protection through  cutting-edge DNA repair, encapsulated sunscreen and antioxidants – all with deep hydration in one effortless step.

The formula centres around next-generation encapsulated filters providing SPF 50 and ultra-high UVA protection. While traditional sunscreens can feel greasy, chalky or irritate the skin, Age Defence uses liposomal encapsulation to deliver broad-spectrum protection through a silky, featherlight cream that melts onto skin and wears beautifully under makeup.

More than just protection, it offers active cellular DNA repair, tackling immediate sun-induced DNA damage and working to promote our skin’s natural repair system with DNA repair enzymes: endonuclease and photolyase. These clever molecules help to protect the skin from the visible signs of ageing caused by everyday UV exposure.


  • Endonuclease and Photolyase: DNA repair enzymes designed to scan our DNA for errors caused by UV damage, and effectively repair them to prevent cellular senescence, inflammation and a breakdown of collagen and fibrillin – key drivers of premature ageing.
  • Next Generation Encapsulated Filter Technology: Creates a perfect grid of protection on the skin’s surface for maximum efficacy and 0% systemic absorption.
  • Bilberry Extract & Raspberry Seed Oil: Natural polyphenol antioxidants that help shield the skin from oxidative stress, pollution and visible light damage.
  • Zero white cast or greasy feel: just smooth, breathable all-day hydration

Age Defence has gone through advanced gene expression testing independently carried out by Professor Mark Birch-Machin, a Professor of molecular dermatology and widely recognised as a leading expert in UV-induced cellular damage to human skin and skin ageing.

He discovered:

  • Age Defence prevents UV-induced cellular senescence.

Giving statistically significant complete protection against UV-induced P21 expression.*

  • Age Defence prevents UV-induced inflammation*

Complete reduction of PTGES expression to baseline levels following UV exposure*

  • Age Defence prevents the breakdown of collagen and fibrillin*

Preventing the UV-induced spike in MMP1.

Founder Dr. Clare Kiely from Co. Mayo, says: ”This is the ultimate day cream designed by Dermatologists to do everything with precision, nourish the barrier, shield from UV & repair the damage. We were so impressed with the final formulation we put it through rigorous RNA sequencing tests on skin to prove its impact at a molecular level”

Age Defence Day Moisturising Cream is a new era of daily skincare, combining luxury, science and real clinical impact in a single bottle. It doesn’t just protect your skin, it helps future proof it.

The Skin Diary’s Age Defence Moisturising Day Cream is (RRP: €110.00) available online at www.theskindiary.com and exclusively at The Institute of Dermatologists® in Ballsbridge, The Centre for Restorative Dermatology in Blackrock.

For more information visit www.theskindiary.com.

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*Statistically significant complete protection proven in gene expression analysis on 3D skin equivalents exposed to high intensity UV radiation.